| Celkem nalezeno: 39 záznamů |
Procházková E. , Hřebabecký H., Dejmek M., Šála M., Šmídková M., Tloušťová E., Zborníková E.,
Eyer L.,
Růžek D., Nencka R. (2020) Could 5 '-N and S ProTide analogues work as prodrugs of antiviral agents? Bioorganic&MedicinalChemistryLetters
30: 126897.
DOI: 10.1016/j.bmcl.2019.126897
|
Salát J., Mikulášek K., Larralde O., Pokorná Formanová P., Chrdle A., Haviernik J.,
Elsterová J., Teislerová D.,
Palus M.,
Eyer L., Zdráhal Z., Petrik J.,
Růžek D. (2020) Tick-Borne Encephalitis Virus Vaccines Contain Non-Structural Protein 1 Antigen and may Elicit NS1-Specific Antibody Responses in Vaccinated Individuals. Vaccines
8: 81.
DOI: 10.3390/vaccines8010081
|
Štefánik M.,
Valdés J. J., Ezebuo F.C., Haviernik J., Uzochukwu I.C., Fojtikova M., Salát J.,
Eyer L.,
Růžek D. (2020) FDA-Approved Drugs Efavirenz, Tipranavir, and Dasabuvir Inhibit Replication of Multiple Flaviviruses in Vero Cells Microorganisms
8: 599.
DOI: 10.3390/microorganisms8040599
|
Eyer L., Fojtikova M., Nencka R., Rudolf I., Hubálek Z.,
Růžek D. (2019) Viral RNA-Dependent RNA Polymerase Inhibitor 7-Deaza-2'-C-Methyladenosine Prevents Death in a Mouse Model of West Nile Virus Infection Antimicrobial Agents and Chemotherapy
63: e02093-18.
DOI: 10.1128/AAC.02093-18
|
Eyer L., Nougairède A., Uhlířová M., Driouich J.S., Zouharova D.,
Valdés J. J., Haviernik J., Gould E., De Clercq E., de Lamballerie X.,
Růžek D. (2019) An E460D Substitution in the NS5 Protein of Tick-Borne Encephalitis Virus Confers Resistance to the Inhibitor Galidesivir (BCX4430) and Also Attenuates the Virus for Mice. Journal of Virology
93: pii: e00367-19.
DOI: 10.1128/JVI.00367-19
|
Krol E., Wandzik I., Brzuska G.,
Eyer L.,
Růžek D., Szewczyk B. (2019) Antiviral Activity of Uridine Derivatives of 2-Deoxy Sugars against Tick-Borne Encephalitis Virus Molecules
24: 1129.
DOI: 10.3390/molecules24061129
|
Růžek D., Avšič Županc T., Borde J., Chrdle A.,
Eyer L., Karganova G. , Kholodilov I., Knap N., Kozlovskya L., Matveev A., Miller A., Osoldkin D.I., Överby A.K., Titukonova N. , Tkachev S., Zajkowska J. (2019) Tick-borne encephalitis in Europe and Russia: Review of pathogenesis, clinical features, therapy, and vaccines Antiviral Research
164: 23–51.
DOI: 10.1016/j.antiviral.2019.01.014
|
Eyer L., Nencka R., De Clercq E., Seley-Radtke K.,
Růžek D. (2018) Nucleoside analogs as a rich source of antiviral agents active against arthropod-borne flaviviruses. vAntiviral Chemistry and Chemotherapy
26: 1-28.
DOI: 10.1177/2040206618761299
|
Haviernik J., Štefánik M., Fojtikova M., Kali S., Noël T., Rudolf I., Hubálek Z.,
Růžek D.,
Eyer L. (2018) Arbidol (Umifenovir): A Broad-Spectrum Antiviral Drug That Inhibits Medically Important Arthropod-Borne Flaviviruses. Viruses
10: 184.
DOI: 10.3390/v10040184
|
Salát J., Formanová P., Huňady M.,
Eyer L.,
Palus M.,
Růžek D. (2018) Development and testing of a new tick-borne encephalitis virus vaccine candidate for veterinary use Vaccine
36: 7257–7261.
DOI: 10.1016/j.vaccine.2018.10.034
|
Štefánik M., Formanová P.,
Bílý T.,
Vancová M.,
Eyer L.,
Palus M.,
Salát J., Braconi C. T. , Zanotto De A. P., Gould E.,
Růžek D. (2018) Characterisation of Zika virus infection in primary human astrocytes. BMC Neuroscience BMC Neuroscience
18: 1136.
DOI: 10.1186/s12868-018-0407-2
|
Eyer L., Kondo H., Zouharova D., Hirano M.,
Valdés J. J., Muto M., Kasti T., Kobayashi S., Haviernik J., Igarashi M., Kariwa H., Vaculovicova M.,
Černý J., Kizek R., Kröger A., Lienenklaus S., Dejmek M., Nencka R.,
Palus M.,
Salát J., De Clercq E., Yoshii K.,
Růžek D. (2017) Escape of Tick-Borne Flavivirus from 2′-C-Methylated Nucleoside Antivirals Is Mediated by a Single Conservative Mutation in NS5 That Has a Dramatic Effect on Viral Fitness Journal of Virology
91: e01028-17.
DOI: 10.1128/JVI.01028-17
|
Eyer L., Zouharova D., Širmarová J., Fojtikova M., Štefánik M., Haviernik J., Nencka R., De Clercq E.,
Růžek D. (2017) Antiviral activity of the adenosine analogue BCX4430 against West Nile virus and tick-borne flaviviruses Antiviral Research
142: 63-67.
DOI: 10.1016/j.antiviral.2017.03.012
|
Eyer L., Nencka R., Huvarová I.,
Palus M., Alves M., Gould E., De Clercq E.,
Růžek D. (2016) Nucleoside inhibitors of Zika virus Journal of Infectious Diseases
214: 707-711.
DOI: 10.1093/infdis/jiw226
|
Eyer L., Šmídková M., Nencka R., Neča J., Kastl T.,
Palus M., De Clercq E.,
Růžek D. (2016) Structure-activity relationships of nucleoside analogues for inhibition of tick-borne encephalitis virus Antiviral Research
133: 119-129.
DOI: 10.1016/j.antiviral.2016.07.018
|
Fernando S., Fernando T., Štefánik M.,
Eyer L.,
Růžek D. (2016) An Approach for Zika Virus Inhibition Using Homology Structure of the Envelope Protein Molecular Biotechnology
58: 801-806.
DOI: 10.1007/s12033-016-9979-1
|
Zouharova D., Lipenska I., Fojtikova M., Kulich P., Neca J., Slaný M., Kovařčík K., Turanek-Knotigova P., Hubatka F., Celechovska H., Masek J., Koudelka S., Prochazka L.,
Eyer L., Plockova J., Bartheldyova E., Miller A.,
Růžek D., Raska M., Janeba Z., Turánek J. (2016) Antiviral activities of 2,6-diaminopurine-based acyclic nucleoside phosphonates against herpesviruses: In vitro study results with pseudorabies virus (PrV, SuHV-1) Veterinary microbiology
184: 84-93.
DOI: 10.1016/j.vetmic.2016.01.010
|
Bílý T.,
Palus M.,
Eyer L.,
Elsterová J.,
Vancová M.,
Růžek D. (2015) Electron tomography analysis of tick-borne encephalitis virus infection in human neurons Scientific Reports
5: 10745.
DOI: 10.1038/srep10745
|
Eyer L.,
Valdés J. J., Gil V., Nencka R., Hřebabecký H., Šála M.,
Salát J.,
Černý J.,
Palus M., De Clercq E.,
Růžek D. (2015) Nucleoside inhibitors of tick-borne encephalitis virus Antimicrobial Agents and Chemotherapy
59: 5483-5493.
DOI: 10.1128/AAC.00807-15
|
