Publications

Total found: 62 records
Perlíková P., Krajczyk A., Doleželová E., Slapničková M., Milisavljevic N., Slavětínská L.P., Tloušt'ová E., Gurská S., Džubák P., Hajdúch M., Panicucci Zíková A., Hocek M. (2021) Synthesis and Antitrypanosomal Activity of 6-Substituted 7-Methyl-7-deazapurine Nucleosides ACS Infectious Diseases 7: 917–926.
DOI: 10.1021/acsinfecdis.1c00062
Serricchio M., Hierro-Yap C., Schädeli D., Hamidane H.B., Hemphill A., Graumann J., Panicucci Zíková A., Bütikofer P. (2021) Depletion of cardiolipin induces major changes in energy metabolism in Trypanosoma brucei bloodstream forms Faseb Journal 35: e21176.
DOI: 10.1096/fj.202001579RR
Tobiasson V., Gahura O., Aibara S., Baradaran R., Panicucci Zíková A., Amunts A. (2021) Interconnected assembly factors regulate the biogenesis of mitoribosomal large subunit Embo Journal e106292.
DOI: 10.1101/2020.06.28.176446
Villafraz O., Biran M., Pineda E., Plazolles N., Cahoreau E., Ornitz Oliveira Souza R., Thonnus M., Allmann S., Tetaud E., Rivière L., Silber A.M., Barrett M.P., Zíková A., Boshart M., Portais J.C., Bringaud F. (2021) Procyclic trypanosomes recycle glucose catabolites and TCA cycle intermediates to stimulate growth in the presence of physiological amounts of proline PLoS Pathogens 17: 1009204.
DOI: 10.1371/journal.ppat.1009204
Aphasizheva I., Alfonzo J., Carnes J., Cruz-Reyes J., Göringer H.U., Hajduk S., Lukeš J., Madison-Antenucci S., Maslov D., Mcdermott S., Ochsenreiter T., Read L., Salavati R., Schnaufer A., Schneider A., Simpson L., Stuart K., Yurchenko V., Zhou Z.H., Panicucci Zíková A., Zhang L., Zimmer S., Aphasizhev R. (2020) Lexis and Grammar of Mitochondrial RNAProcessing in Trypanosomes Trends in Parasitology 36: 4.
DOI: 10.1016/j.pt.2020.01.006

Documents to download:
Aphasizheva_2020_TrendsinParasitology (pdf)
Doleželová E., Kunzová M., Dejung M., Levin M., Panicucci B., Regnault C., Janzen C., Barrett M.P., Butter F., Panicucci Zíková A. (2020) Cell-based and multi-omics profiling reveals dynamic metabolic repurposing of mitochondria to drive developmental progression of Trypanosoma brucei Plos Biology 18: e3000741.
DOI: 10.1371/journal.pbio.3000741
Smith J.T., Doleželová E., Tylec B., Bard J.E., Chen R., Sun Y., Panicucci Zíková A., Read L. (2020) Developmental regulation of edited CYb and COIII mitochondrial mRNAs is achieved by distinct mechanisms in Trypanosoma brucei Nucleic Acids Research 48: 8704–8723.
DOI: 10.1093/nar/gkaa641
Zoltner M., Campagnaro G.D., Taleva G., Burrell A., Cerone M., Leung K., Achcar F., Horn D., Vaughan S., Gadelha C., Panicucci Zíková A., Barrett M.P., de Koning H., Field M. (2020) Suramin exposure alters cellular metabolism and mitochondrial energy production in African trypanosomes Journal of Biological Chemistry 295: 8331-8347.
DOI: 10.1074/jbc.RA120.012355

Documents to download:
Zoltner_2020_JBC (pdf)
Gahura O., Panicucci Zíková A. (2019) Isolation of F1-ATPase from the Parasitic Protist Trypanosoma brucei Journal of visualized experiments : JoVE 22: e58334.
DOI: 10.3791/58334
Nenarokova A., Záhonová K., Krasilnikova M., Gahura O., McCulloch R., Zíková A., Yurchenko V., Lukeš J. (2019) Causes and effects of loss of classical nonhomologous end joining pathway in parasitic eukaryotes mBio 10: e01541-19.
DOI: 10.1128/mBio.01541-19

Documents to download:
Nenarokova_et al._2019 (pdf)
Terán D., Doleželová E., Keough D., Hocková D., Panicucci Zíková A., Guddat L. (2019) Crystal structures of Trypanosoma brucei hypoxanthine – guanine – xanthine phosphoribosyltransferase in complex with IMP, GMP and XMP FEBS Journal 286: 4721-4736.
DOI: 10.1017/S0022149X19000737
Doleželová E., Terán D., Gahura O., Kotrbová Z., Procházková M., Keough D., Špaček P., Hocková D., Guddat L., Zíková A. (2018) Evaluation of the Trypanosoma brucei 6-oxopurine salvage pathway as a potential target for drug discovery PLOS Neglected Tropical Diseases DOI: 10.1371/journal.pntd.0006301
Gahura O., Panicucci B., Váchová Hana, Walker John E., Zíková A. (2018) Inhibition of F1 -ATPase from Trypanosoma brucei by its regulatory protein inhibitor TbIF1 FEBS Journal DOI: 10.1111/febs.14672
Gahura O., Šubrtová , Váchová Hana, Panicucci B., Fearnley Ian M., Harbour Michael E., Walker John E., Zíková A. (2018) The F1 -ATPase from Trypanosoma brucei is elaborated by three copies of an additional p18-subunit FEBS Journal 285: 614-628.
DOI: 10.1111/febs.14364
Montgomery M.G., Gahura O., Leslie A.G., Zíková A., Walker J.E. (2018) ATP synthase from Trypanosoma brucei has an elaborated canonical F1-domain and conventional catalytic sites. Proceedings of the National Academy of Sciences of the United States of America 115: 2102-2107.
DOI: 10.1073/pnas.1720940115
Procházková M., Panicucci B., Panicucci Zíková A. (2018) Cultured bloodstream Trypanosoma brucei adapt to life without mitochondrial translation release factor 1 Scientific Reports 8: 5135.
DOI: 10.1038/s41598-018-23472-6
Panicucci B., Gahura O., Zíková A. (2017) Trypanosoma brucei TbIF1 inhibits the essential F1-ATPase in the infectious form of the parasite PloS Neglected Tropical Diseases 11: e0005552.
DOI: 10.1371/journal.pntd.0005552
Zíková A., Verner Z., Nenarokova A., Michels P.A.M., Lukeš J. (2017) A paradigm shift: The mitoproteomes of procyclic and bloodstream Trypanosoma brucei are comparably complex PLOS Pathogens 13: e1006679.
DOI: 10.1371/journal.ppat.1006679

Documents to download:
Zikova et al. 2017 PLOS Pathogens (pdf)
Alkhaldi A., Martinek J., Panicucci B., Dardonville C., Zíková A., de Koning H. (2016) Trypanocidal action of bisphosphonium salts through a mitochondrial target in bloodstream form Trypanosoma brucei International Journal for Parasitology: Drugs and Drug Resistance 6: 23-34.
DOI: 10.1016/j.ijpddr.2015.12.002
Hashimi H., Kaltenbrunner S., Zíková A., Lukeš J. (2016) Trypanosome Mitochondrial Translation and Tetracycline: No Sweat about Tet PLoS Pathogens 12: e1005492.
DOI: 10.1371/journal.ppat.1005492

Documents to download:
Hashimi et al. 2016 PLoS Pathog (pdf)

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