Foto: The black-legged or deer tick (Ixodes scapularis) is responsible for transmitting Lyme disease in the northeast, mid-Atlantic, and north-central United States. Image credit: Shutterstock/Steven Ellingson. LYMErix was on the market for just four years. Concerns over adverse reactions and a lukewarm reception from public health agencies led the vaccine’s...
The general mRNA exporters Mex67 and Mtr2 play distinct roles in nuclear export of tRNAs in Trypanosoma brucei . Transfer RNAs (tRNAs) are central players in protein synthesis, which in Eukarya need to be delivered from the nucleus to the cytoplasm by specific transport receptors, most of which belong to the evolutionarily conserved beta-importin family. Based on the available...
Cryptosporidium occultus by Bohumil Sak, Nikola Holubová and Martin Kváč was an accompanying hero image to the article Kissinger 2019: Evolution of Cryptosporidium . Nature Microbiology 4: 730–731. [IF=14.300]
Systems biology approaches, especially in the big data era, have revolutionized modern parasitology. Of the many different molecules participating in parasite–host interactions, noncoding RNAs (ncRNAs) are now known to be (i) transmitted by the vector to possibly modulate vertebrate host responses and favor vector survival and (ii) regulated in the host by parasites to favor parasite survival....
"Characterization and Use of Genetically Encoded Fluorescent Heme Sensors to Interrogate Heme Trafficking, Dynamics and Signaling"
The 2019 tables are based on Nature Index data from 1 January 2018 to 31 December 2018. The normalized ranking is derived by calculating the ratio of FC to the institution’s total article output in natural sciences as tracked by the Dimensions database from Digital Science.