We detected Leishmania infantum infection in 45% of tigers and 5.3% of sand flies tested at a zoo in southern Italy in 2019. These infections in tigers and the abundance of Phlebotomus perniciosus sand flies represent a potential risk to other animals and humans living in or visiting the zoo.
Abstract Mitochondrial metabolic remodeling is a hallmark of the Trypanosoma brucei digenetic life cycle because the insect stage utilizes a cost-effective oxidative phosphorylation (OxPhos) to generate ATP, while bloodstream cells switch to aerobic glycolysis. Due to difficulties in acquiring enough parasites from the tsetse fly vector, the dynamics of the parasite’s metabolic rewiring in the...
The French biotech Valneva will collaborate with Pfizer to develop and commercialize Valneva’s phase II-stage Lyme disease vaccine candidate. The deal they signed is expected to help compensate for the impact of the Covid-19 pandemic on Valneva’s financial outlook for 2020.
Researchers from the Biology Center of the Czech Academy of Science say that a vaccine against Lyme disease has shown 100% effectiveness in tests. The results were published at the beginning of May in NPJ Vaccines, a partner journal of Nature.
Researchers have found that molecules from ticks called Evasins have the potential to halt cytokine storms, the leading cause of COVID-19 fatalities.
Engineered Plasmodium parasites form the basis of two experimental malaria vaccines that showed safety and encouraging immune responses in clinical trials. by Ruth Williams
More K., Klinger C.M., Barlow L.D., Dacks J.B. 2020: Evolution and natural history of membrane trafficking. Current Biology 30: R553–R564.
Pánek T., Eliáš M., Vancová M., Lukeš J., Hashimi H. 2020: Returning to the fold for lessons in mitochondrial crista diversity and evolution. Current Biology 30: R575–R588
Genetic tool development in marine protists: emerging model organisms for experimental cell biology Abstract Diverse microbial ecosystems underpin life in the sea. Among these microbes are many unicellular eukaryotes that span the diversity of the eukaryotic tree of life. However, genetic tractability has been limited to a few species, which do not represent eukaryotic...
Molecular parasitologist Zdeněk Paris successfully cured from Covid-19. He returns to work to help colleagues with testing the clinical samples on this disease.
